Ontology highlight
ABSTRACT:
SUBMITTER: Patterson B
PROVIDER: S-EPMC5738034 | biostudies-other | 2017 Dec
REPOSITORIES: biostudies-other
Tissue engineering and regenerative medicine 20171122 6
Recent advances in stem cell biology have dramatically increased the understanding of molecular and cellular mechanism of pluripotency and cell fate determination. Additionally, pluripotent stem cells (PSCs), including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), arose as essential resources for disease modeling and cellular therapeutics. Despite these advancements, the epigenetic dysregulation in pluripotency such as the imprinting status, and X chromosome dosage comp ...[more]