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Data on a single oral dose of camu camu (Myrciaria dubia) pericarp extract on flow-mediated vasodilation and blood pressure in young adult humans.

ABSTRACT: This data article describes the flow-mediated vasodilation (FMD) responses, represented by changes in arterial diameter, and blood pressure changes in young adults after a single oral dose of camu camu (Myrciaria dubia) pericarp extract or placebo (cross-over design). Ten healthy men and 10 healthy women participated in this study. Ultrasonic diagnostic equipment was used to monitor arterial diameter changes, indicative of FMD, for 110 s after the administration of the camu camu extract or placebo. In addition, the systolic and diastolic blood pressure values were recorded.

SUBMITTER: Miyashita T

PROVIDER: S-EPMC5752086 | biostudies-other | 2018 Feb

REPOSITORIES: biostudies-other

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Data on a single oral dose of camu camu (<i>Myrciaria dubia</i>) pericarp extract on flow-mediated vasodilation and blood pressure in young adult humans.

Miyashita Tadayoshi T Koizumi Ryosuke R Myoda Takao T Sagane Yoshimasa Y Niwa Koichi K Watanabe Toshihiro T Minami Kazuhiro K

Data in brief 20171214

This data article describes the flow-mediated vasodilation (FMD) responses, represented by changes in arterial diameter, and blood pressure changes in young adults after a single oral dose of camu camu (<i>Myrciaria dubia</i>) pericarp extract or placebo (cross-over design). Ten healthy men and 10 healthy women participated in this study. Ultrasonic diagnostic equipment was used to monitor arterial diameter changes, indicative of FMD, for 110 s after the administration of the camu camu extract o ...[more]

PMID: 29322080

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Project description:The effect of nitrate (NO3-) supplementation on blood pressure (BP) responses during large muscle mass isometric and ischaemic exercise in healthy young adults is unclear. The aim of the present study was to assess the effect of 5-day supplementation of NO3- on BP responses during a short isometric contraction and a sustained ischaemic contraction. In a randomised, double-blinded, crossover design, 14 healthy active young adults underwent BP measurements after 5 days of either NO3- (NIT) or placebo (PLA) supplementation. Beat-by-beat BP was measured at pre- and post-exercise rest, and during a short (20 s) isometric contraction at 25% maximal strength and throughout a sustained ischaemic contraction. Plasma nitrite (NO2-) concentration increased significantly after NO3- supplementation compared to placebo (475 ± 93 nmol·L-1 vs. 198 ± 46 nmol·L-1, p < 0.001, d = 3.37). Systolic BP was significantly lower at pre- (p = 0.051) and post-exercise rest (p = 0.006), during a short isometric contraction (p = 0.030), and throughout a sustained ischaemic contraction (p = 0.040) after NO3- supplementation. Mean arterial pressure was significantly lower at pre- (p = 0.004) and post-exercise rest (p = 0.043), during a short isometric contraction (p = 0.041), and throughout a sustained ischaemic contraction (p = 0.021) after NO3- supplementation. Diastolic BP was lower at pre-exercise rest (p = 0.032), but not at post-exercise rest, during a short isometric contraction, and during a sustained ischaemic contraction (all p > 0.05). Five days of NO3- supplementation elevated plasma NO2- concentration and reduced BP during a short isometric contraction and a sustained ischaemic contraction in healthy adults. These observations indicate that multiple-day nitrate supplementation can decrease BP at rest and attenuate the increased BP response during isometric exercise. These findings support that NO3- supplementation is an effective nutritional intervention in reducing SBP and MAP in healthy young males during submaximal exercise.

Dataset Information

Data on a single oral dose of camu camu (Myrciaria dubia) pericarp extract on flow-mediated vasodilation and blood pressure in young adult humans.

Publications

Data on a single oral dose of camu camu (<i>Myrciaria dubia</i>) pericarp extract on flow-mediated vasodilation and blood pressure in young adult humans.

Similar Datasets

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