A systematic review and meta-analysis: Association between MGMT hypermethylation and the clinicopathological characteristics of non-small-cell lung carcinoma.
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ABSTRACT:
SUBMITTER: Chen L
PROVIDER: S-EPMC5780517 | biostudies-other | 2018 Jan
REPOSITORIES: biostudies-other
Publications
A systematic review and meta-analysis: Association between MGMT hypermethylation and the clinicopathological characteristics of non-small-cell lung carcinoma.
Chen Lin L Wang Yong Y Liu Fen F Xu Liyao L Peng Feifei F Zhao Ning N Fu Biqi B Zhu Zijie Z Shi Yu Y Liu Jiansheng J Wu Renrui R Wang Chen C Yao Shengmin S Li Yong Y
Scientific reports 20180123 1
The relationship between O-6-methylguanine-DNA methyltransferase (MGMT) promoter methylation and clinicopathological characteristics of non-small-cell lung carcinoma (NSCLC) has remained controversial and unclear. Therefore, in this study we have undertaken a systematic review and meta-analysis of relevant studies to quantitatively investigate this association. We identified 30 eligible studies investigating 2714 NSCLC patients. The relationship between MGMT hypermethylation and NSCLC was identi ...[more]
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