Updates on Immune Therapies in Type 1 Diabetes.
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ABSTRACT:
SUBMITTER: Nambam B
PROVIDER: S-EPMC5813448 | biostudies-other | 2016 Aug
REPOSITORIES: biostudies-other
Publications
Updates on Immune Therapies in Type 1 Diabetes.
Nambam Bimota B Haller Michael J MJ
European endocrinology 20160828 2
Multiple clinical trials investigating the efficacy and safety of immunotherapeutic interventions in new onset type 1 diabetes (T1D) have failed to yield long term clinical benefit. Lack of efficacy has frequently been attributed to an incomplete understanding of the pathways involved in T1D and the use of single immunotherapeutic agents. Recent mechanistic studies have improved our knowledge of the complex etiopathogenesis of T1D. This in turn has provided the framework for new and ongoing clin ...[more]
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