Ontology highlight
ABSTRACT:
SUBMITTER: Katakami N
PROVIDER: S-EPMC5814824 | biostudies-other | 2018 Feb
REPOSITORIES: biostudies-other
Katakami Nobuyuki N Uchino Junji J Yokoyama Takuma T Naito Tateaki T Kondo Masashi M Yamada Kouzo K Kitajima Hiromoto H Yoshimori Kozo K Sato Kazuhiro K Saito Hiroshi H Aoe Keisuke K Tsuji Tetsuya T Takiguchi Yuichi Y Takayama Koichi K Komura Naoyuki N Takiguchi Toru T Eguchi Kenji K
Cancer 20171204 3
<h4>Background</h4>Cachexia, described as weight loss (mainly in lean body mass [LBM]) and anorexia, is common in patients with advanced cancer. This study examined the efficacy and safety of anamorelin (ONO-7643), a novel selective ghrelin receptor agonist, in Japanese cancer patients with cachexia.<h4>Methods</h4>This double-blind clinical trial (ONO-7643-04) enrolled 174 patients with unresectable stage III/IV non-small cell lung cancer (NSCLC) and cachexia in Japan. Patients were randomized ...[more]