Ontology highlight
ABSTRACT:
SUBMITTER: Xu L
PROVIDER: S-EPMC5815282 | biostudies-other | 2018
REPOSITORIES: biostudies-other
Xu Lingjun L Han Shuwen S Yan Linjie L Wang Haifeng H Peng Haihui H Chen Fener F
Beilstein journal of organic chemistry 20180131
A family of novel chloramphenicol base-amide organocatalysts possessing a NH functionality at C-1 position as monodentate hydrogen bond donor were developed and evaluated for enantioselective organocatalytic alcoholysis of <i>meso</i>-cyclic anhydrides. These structural diversified organocatalysts were found to induce high enantioselectivity in alcoholysis of anhydrides and was successfully applied to the asymmetric synthesis of (<i>S</i>)-GABOB. ...[more]