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Completion lymphadenectomy for sentinel node positive cutaneous head & neck melanoma.


ABSTRACT: The application and utility of melanoma sentinel lymph node biopsy (SLNB) has evolved significantly since its inception over two decades ago. The current focus has shifted from a staging modality to potentially a therapeutic intervention. Recent research to include large multi-institutional randomized trials have attempted to answer the question: is a completion lymph node dissection (CLND) required following a positive SLNB? This review provides an evidence-based, contemporary review of the utility of CLND for SLNB positive head and neck cutaneous melanoma patients.NA.

SUBMITTER: Schmalbach CE 

PROVIDER: S-EPMC5824115 | biostudies-other | 2018 Feb

REPOSITORIES: biostudies-other

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Completion lymphadenectomy for sentinel node positive cutaneous head & neck melanoma.

Schmalbach Cecelia E CE   Bradford Carol R CR  

Laryngoscope investigative otolaryngology 20180205 1


The application and utility of melanoma sentinel lymph node biopsy (SLNB) has evolved significantly since its inception over two decades ago. The current focus has shifted from a staging modality to potentially a therapeutic intervention. Recent research to include large multi-institutional randomized trials have attempted to answer the question: is a completion lymph node dissection (CLND) required following a positive SLNB? This review provides an evidence-based, contemporary review of the uti  ...[more]

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