Dataset Information
Alkene 1,2-Difunctionalization by Radical Alkenyl Migration.
Ontology highlight
ABSTRACT:
SUBMITTER: Tang X
PROVIDER: S-EPMC5838557 | biostudies-other | 2018 Jan
REPOSITORIES: biostudies-other
Publications
Alkene 1,2-Difunctionalization by Radical Alkenyl Migration.
Angewandte Chemie (International ed. in English) 20171214 3
Transition-metal-free radical α-perfluoroalkylation with the accompanying vicinal β-alkenylation of unactivated alkenes is presented. These radical cascades proceed by means of 1,4- or 1,5-alkenyl migration by electron catalysis on readily accessed allylic alcohols. The reactions comprise a regioselective perfluoroalkyl radical addition with subsequent alkenyl migration and concomitant deprotonation to generate a ketyl radical anion that sustains the chain as a single-electron-transfer reducing ...[more]