Ontology highlight
ABSTRACT:
SUBMITTER: Ogg MC
PROVIDER: S-EPMC5951802 | biostudies-other | 2018 May
REPOSITORIES: biostudies-other
Ogg M Cameron MC Ross Jordan M JM Bendahmane Mounir M Fletcher Max L ML
Nature communications 20180514 1
Habituation and dishabituation modulate the neural resources and behavioral significance allocated to incoming stimuli across the sensory systems. We characterize these processes in the mouse olfactory bulb (OB) and uncover a role for OB acetylcholine (ACh) in physiological and behavioral olfactory dishabituation. We use calcium imaging in both awake and anesthetized mice to determine the time course and magnitude of OB glomerular habituation during a prolonged odor presentation. In addition, we ...[more]