Two-photon imaging of neuronal activity in motor cortex of marmosets during upper-limb movement tasks.
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ABSTRACT:
SUBMITTER: Ebina T
PROVIDER: S-EPMC5951821 | biostudies-other | 2018 May
REPOSITORIES: biostudies-other
Publications
Two-photon imaging of neuronal activity in motor cortex of marmosets during upper-limb movement tasks.
Ebina Teppei T Masamizu Yoshito Y Tanaka Yasuhiro R YR Watakabe Akiya A Hirakawa Reiko R Hirayama Yuka Y Hira Riichiro R Terada Shin-Ichiro SI Koketsu Daisuke D Hikosaka Kazuo K Mizukami Hiroaki H Nambu Atsushi A Sasaki Erika E Yamamori Tetsuo T Matsuzaki Masanori M
Nature communications 20180514 1
Two-photon imaging in behaving animals has revealed neuronal activities related to behavioral and cognitive function at single-cell resolution. However, marmosets have posed a challenge due to limited success in training on motor tasks. Here we report the development of protocols to train head-fixed common marmosets to perform upper-limb movement tasks and simultaneously perform two-photon imaging. After 2-5 months of training sessions, head-fixed marmosets can control a manipulandum to move a c ...[more]
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