Ontology highlight
ABSTRACT:
SUBMITTER: Hems ES
PROVIDER: S-EPMC5999359 | biostudies-other | 2018 Jun
REPOSITORIES: biostudies-other
Carbohydrate research 20180417
A suite of glycosylated glycerol derivatives representing various fragments of the glycosylated ichthyotoxins called prymnesins were chemically synthesised. Glycerol was used to represent a small fragment of the prymnesin backbone, and was glycosylated at the 2° position with the sugars currently reported to be present on prymnesin toxins. Neighbouring group participation was utilised to synthesise 1,2-trans-glycosides. SnCl<sub>2</sub>-promoted glycosylation with furanosyl fluorides gave 1,2-ci ...[more]