Review of cariprazine in management of psychiatric illness.
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ABSTRACT:
SUBMITTER: Campbell RH
PROVIDER: S-EPMC6007710 | biostudies-other | 2017 Sep
REPOSITORIES: biostudies-other
Publications
Review of cariprazine in management of psychiatric illness.
Campbell Rebecca H RH Diduch Michael M Gardner Kristen N KN Thomas Christopher C
The mental health clinician 20170901 5
Schizophrenia and bipolar disorder are severe and debilitating psychiatric disorders. Despite the availability of numerous antipsychotic drugs, many patients still experience poor outcomes and treatment-limiting adverse side effects. Cariprazine is a novel antipsychotic with unique pharmacodynamic and pharmacokinetic properties. It is both a dopamine type 2 and dopamine type 3 partial agonist with 2 equipotent metabolites, desmethyl cariprazine and didesmethyl cariprazine, of which didesmethyl c ...[more]
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