Ontology highlight
ABSTRACT:
SUBMITTER: Morizur L
PROVIDER: S-EPMC6092681 | biostudies-other | 2018 Aug
REPOSITORIES: biostudies-other
Stem cell reports 20180705 2
Deciphering the mechanisms that regulate the quiescence of adult neural stem cells (NSCs) is crucial for the development of therapeutic strategies based on the stimulation of their endogenous regenerative potential in the damaged brain. We show that LeX<sup>bright</sup> cells sorted from the adult mouse subventricular zone exhibit all the characteristic features of quiescent NSCs. Indeed, they constitute a subpopulation of slowly dividing cells that is able to enter the cell cycle to regenerate ...[more]