Ontology highlight
ABSTRACT:
SUBMITTER: Wijnenga MMJ
PROVIDER: S-EPMC6096891 | biostudies-other | 2018 Sep
REPOSITORIES: biostudies-other
Wijnenga Maarten M J MMJ French Pim J PJ Dubbink Hendrikus J HJ Dinjens Winand N M WNM Atmodimedjo Peggy N PN Kros Johan M JM Fleischeuer Ruth R Dirven Clemens M F CMF Vincent Arnaud J P E AJPE van den Bent Martin J MJ
Journal of neuro-oncology 20180416 2
<h4>Background</h4>At current prognostication of low grade glioma remains suboptimal and might be improved with additional markers. These may guide treatment decisions, in particular on early adjuvant therapy versus wait and see after surgery.<h4>Methods</h4>We used a targeted Next-Generation Sequencing panel to assess mutational and copy number status of selected genes and chromosomes in a consecutive series of adult grade II supratentorial glioma, and assessed the impact of molecular markers o ...[more]