Unknown

Dataset Information

0

Straightforward Synthesis of Bifunctional Phosphorus Phenols via Phosphination of In Situ Generated o-Quinone Methides.


ABSTRACT: An efficient and practical approach towards bifunctional phosphorus phenols has been developed through a reaction of diphenylphosphine oxide and the o-quinone methides in situ generated from 2-tosylalkyl phenols under basic conditions. This protocol features simple experimental procedures under mild conditions and is easily scaled up. With this method, a variety of diarylmethyl phosphine oxides can be produced with up to 92% yield.

SUBMITTER: Chen Z 

PROVIDER: S-EPMC6100389 | biostudies-other | 2018 May

REPOSITORIES: biostudies-other

altmetric image

Publications

Straightforward Synthesis of Bifunctional Phosphorus Phenols via Phosphination of In Situ Generated <i>o</i>-Quinone Methides.

Chen Zhangpei Z   Shi Qinglong Q   Wang Gongshu G   Chen Siwen S   Hu Jianshe J  

Molecules (Basel, Switzerland) 20180523 6


An efficient and practical approach towards bifunctional phosphorus phenols has been developed through a reaction of diphenylphosphine oxide and the <i>o</i>-quinone methides in situ generated from 2-tosylalkyl phenols under basic conditions. This protocol features simple experimental procedures under mild conditions and is easily scaled up. With this method, a variety of diarylmethyl phosphine oxides can be produced with up to 92% yield. ...[more]

Similar Datasets

| S-EPMC5419452 | biostudies-literature
| S-EPMC6217962 | biostudies-literature
| S-EPMC9737762 | biostudies-literature
| S-EPMC6644540 | biostudies-literature
| S-EPMC7839490 | biostudies-literature
| S-EPMC9486948 | biostudies-literature
| S-EPMC6717626 | biostudies-literature
| S-EPMC9057278 | biostudies-literature
| S-EPMC3250381 | biostudies-literature