Dataset Information
Straightforward Synthesis of Bifunctional Phosphorus Phenols via Phosphination of In Situ Generated o-Quinone Methides.
Ontology highlight
ABSTRACT:
SUBMITTER: Chen Z
PROVIDER: S-EPMC6100389 | biostudies-other | 2018 May
REPOSITORIES: biostudies-other
Publications
Straightforward Synthesis of Bifunctional Phosphorus Phenols via Phosphination of In Situ Generated <i>o</i>-Quinone Methides.
Molecules (Basel, Switzerland) 20180523 6
An efficient and practical approach towards bifunctional phosphorus phenols has been developed through a reaction of diphenylphosphine oxide and the <i>o</i>-quinone methides in situ generated from 2-tosylalkyl phenols under basic conditions. This protocol features simple experimental procedures under mild conditions and is easily scaled up. With this method, a variety of diarylmethyl phosphine oxides can be produced with up to 92% yield. ...[more]