Sex Differences in HIV Infection: Mystique Versus Machismo.
Ontology highlight
ABSTRACT:
SUBMITTER: Scully EP
PROVIDER: S-EPMC6103226 | biostudies-other | 2018
REPOSITORIES: biostudies-other
Publications
Sex Differences in HIV Infection: Mystique Versus Machismo.
Pathogens & immunity 20180713 1
Biological sex is a determinant of both susceptibility to and pathogenesis of multiple infections, including HIV. These differences have effects on the spectrum of HIV disease from acquisition to eradication, with diverse mechanisms including distinct chromosomal complements, variation in microbiota composition, hormonal effects on transcriptional profiles, and expression of different immunoregulatory elements. With a comparative biology approach, these sex differences can be used to highlight p ...[more]
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