Ontology highlight
ABSTRACT:
SUBMITTER: Kong P
PROVIDER: S-EPMC6192997 | biostudies-other | 2018 Oct
REPOSITORIES: biostudies-other
Cell death & disease 20181017 11
Triple-negative breast cancer (TNBC) has a poorer outcome than other subtypes of breast cancer, and the discovery of dysregulated microRNA (miRNA) and their role in tumor progression has provided a new avenue for elucidating the mechanism involved in TNBC. In this study, we identified that miR-3178 was significantly reduced in TNBC, and the low miR-3178 expression correlated with poor overall survival in TNBC but not in non-TNBC. The ectopic overexpression of miR-3178 suppressed TNBC cell prolif ...[more]