Ontology highlight
ABSTRACT:
SUBMITTER: Li R
PROVIDER: S-EPMC6200095 | biostudies-other | 2018
REPOSITORIES: biostudies-other
Li Rong R Chibbar Rajni R Xiang Jim J
OncoTargets and therapy 20181017
Breast cancer is the leading cause of death in women globally. The human epidermal growth factor receptor 2 (HER2)-positive breast cancer is often associated with poor prognosis and high mortality. Even though anti-HER2 monoclonal antibodies have improved the clinical outcome, resistance to the antibody therapy becomes a major obstacle in the treatment of HER2-positive breast cancer patients. Alternative approaches are therefore needed. HER2-specific vaccines have been developed to trigger patie ...[more]