Ontology highlight
ABSTRACT:
SUBMITTER: Farnoodian M
PROVIDER: S-EPMC6210860 | biostudies-other | 2018 Oct-Dec
REPOSITORIES: biostudies-other
Farnoodian Mitra M Sorenson Christine M CM Sheibani Nader N
Journal of ophthalmic & vision research 20181001 4
Angiogenesis, the formation of new blood vessels from pre-existing capillaries, is very tightly regulated and normally does not occur except during developmental and reparative processes. This tight regulation is maintained by a balanced production of positive and negative regulators, and alterations under pathological conditions such as retinopathy of prematurity, diabetic retinopathy, and age-related macular degeneration can lead to growth of new and abnormal blood vessels. Although the role o ...[more]