Lipoprotein markers associated with disability from multiple sclerosis.
Ontology highlight
ABSTRACT:
SUBMITTER: Gafson AR
PROVIDER: S-EPMC6242870 | biostudies-other | 2018 Nov
REPOSITORIES: biostudies-other
Publications
Lipoprotein markers associated with disability from multiple sclerosis.
Gafson A R AR Thorne T T McKechnie C I J CIJ Jimenez B B Nicholas R R Matthews P M PM
Scientific reports 20181119 1
Altered lipid metabolism is a feature of chronic inflammatory disorders. Increased plasma lipids and lipoproteins have been associated with multiple sclerosis (MS) disease activity. Our objective was to characterise the specific lipids and associated plasma lipoproteins increased in MS and to test for an association with disability. Plasma samples were collected from 27 RRMS patients (median EDSS, 1.5, range 1-7) and 31 healthy controls. Concentrations of lipids within lipoprotein sub-classes we ...[more]
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