Air pollutant particulate matter 2.5 induces dry eye syndrome in mice.
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ABSTRACT:
SUBMITTER: Tan G
PROVIDER: S-EPMC6292905 | biostudies-other | 2018 Dec
REPOSITORIES: biostudies-other
Publications
Air pollutant particulate matter 2.5 induces dry eye syndrome in mice.
Tan Gang G Li Juan J Yang Qichen Q Wu Anhua A Qu Dong-Yi DY Wang Yahong Y Ye Lei L Bao Jing J Shao Yi Y
Scientific reports 20181213 1
In this study, we explored the effects of particulate matter 2.5 (PM<sub>2.5</sub>) eye drops on the ocular surface structure and tear function in mice and established a novel animal model for dry eye research. We found that, following treatment with PM<sub>2.5</sub>, the tear volume and, the tear film break-up time showed statistical differences at each time point (P < 0.05). The FL score of the PM<sub>2.5</sub>-treated group was higher than that of others (P < 0.05). The average number of corn ...[more]
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