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Pharmacological effects of berberine on mood disorders.


ABSTRACT: Berberine, a natural isoquinoline alkaloid, is used in herbal medicine and has recently been shown to have efficacy in the treatment of mood disorders. Furthermore, berberine modulates neurotransmitters and their receptor systems within the central nervous system. However, the detailed mechanisms of its action remain unclear. This review summarizes the pharmacological effects of berberine on mood disorders. Therefore, it may be helpful for potential application in the treatment of mood disorders.

SUBMITTER: Fan J 

PROVIDER: S-EPMC6307759 | biostudies-other | 2019 Jan

REPOSITORIES: biostudies-other

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Pharmacological effects of berberine on mood disorders.

Fan Jie J   Zhang Kun K   Jin Yang Y   Li Bingjini B   Gao Shuohui S   Zhu Jiaming J   Cui Ranji R  

Journal of cellular and molecular medicine 20181118 1


Berberine, a natural isoquinoline alkaloid, is used in herbal medicine and has recently been shown to have efficacy in the treatment of mood disorders. Furthermore, berberine modulates neurotransmitters and their receptor systems within the central nervous system. However, the detailed mechanisms of its action remain unclear. This review summarizes the pharmacological effects of berberine on mood disorders. Therefore, it may be helpful for potential application in the treatment of mood disorders  ...[more]

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