Ontology highlight
ABSTRACT:
SUBMITTER: Wei J
PROVIDER: S-EPMC6308085 | biostudies-other | 2018 Dec
REPOSITORIES: biostudies-other
Wei Jingchao J Gan Yu Y Peng Dongyi D Jiang Xianzhen X Kitazawa Riko R Xiang Yali Y Dai Yingbo Y Tang Yuxin Y Yang Jianfu J
Cancer medicine 20181114 12
The role of TDRG1 in tumorigenesis and the progression of seminoma, as well as its role in regulating chemosensitivity of seminoma to cisplatin through the PI3K/Akt/mTOR signaling pathway, has been previously defined. However, the detailed mechanism underlying TDRG1 expression and concomitant chemoresistance conditions are unknown. Furthermore, it has been reported that non-protein-coding RNAs play an important role in a variety of vital processes including cellular chemosensitivity. However, th ...[more]