Ontology highlight
ABSTRACT:
SUBMITTER: Rahim MN
PROVIDER: S-EPMC6316800 | biostudies-other | 2018 Dec
REPOSITORIES: biostudies-other
Rahim Md Niaz MN Klewes Ludger L Zahedi-Amiri Ali A Mai Sabine S Coombs Kevin M KM
Viruses 20181219 12
Influenza A virus (IAV) infections remain a major human health threat. IAV has enormous genetic plasticity and can rapidly escape virus-targeted anti-viral strategies. Thus, there is increasing interest to identify host proteins and processes the virus requires for replication and maturation. The IAV non-structural protein 1 (NS1) is a critical multifunctional protein that is expressed to high levels in infected cells. Host proteins that interact with NS1 may serve as ideal targets for attenuati ...[more]