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Body mass index and its effects on liver fat content in overweight and obese young adults by proton magnetic resonance spectroscopy technique.


ABSTRACT: AIM:To assess the association between liver fat content (LFC) and weight status in young adults using proton magnetic resonance spectroscopy (1H MRS) technique. METHODS:Seventy-eight healthy young adults, between 19-30 years of age participated in this study. This group was then separated into a control of 39 subjects and an overweight/obese group (OW/OB group) consisting of 39 subjects. Blood biochemical quantity and 1H MRS was performed for LFC assessment. RESULTS:LFC was found to be almost three times higher in OW/OB group when compared to the control group. A 48.7% incidence of non-alcoholic fatty liver disease in the OW/OB group was found. Blood biochemical measurements showed statistically higher low-density lipoproteins and triglyceride, lower high-density lipoproteins, and increased glycosylated hemoglobin and fasting glucose in the OW/OB group. Body mass index was a significant independent predictor for LFC after adjusting for age and sex (multiple linear regression; ? = 0.459, P < 0.001). CONCLUSION:Due to the prevalence of high LFC in the OW/OB group, it can be proposed that weight gain and obesity are sensitive indicators of high hepatic fat content.

SUBMITTER: Pasanta D 

PROVIDER: S-EPMC6323521 | biostudies-other | 2018 Dec

REPOSITORIES: biostudies-other

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Body mass index and its effects on liver fat content in overweight and obese young adults by proton magnetic resonance spectroscopy technique.

Pasanta Duanghathai D   Tungjai Montree M   Chancharunee Sirirat S   Sajomsang Warayuth W   Kothan Suchart S  

World journal of hepatology 20181201 12


<h4>Aim</h4>To assess the association between liver fat content (LFC) and weight status in young adults using proton magnetic resonance spectroscopy (<sup>1</sup>H MRS) technique.<h4>Methods</h4>Seventy-eight healthy young adults, between 19-30 years of age participated in this study. This group was then separated into a control of 39 subjects and an overweight/obese group (OW/OB group) consisting of 39 subjects. Blood biochemical quantity and <sup>1</sup>H MRS was performed for LFC assessment.<  ...[more]

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