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Prognostic value of quality-of-life scores in patients with breast cancer undergoing preoperative chemotherapy.


ABSTRACT: Background:Recently, evaluation of quality of life (QOL) has been recognized as a significant outcome measure in the treatment of several cancers. In this study, the Anti-Cancer Drugs-Breast (ACD-B) QOL score was used to assess disease-specific survival in women with breast cancer undergoing preoperative chemotherapy (POC). Methods:QOL-ACD-B scores were evaluated before and after POC. The cut-off value of QOL-ACD-B contributing to events such as relapse or death was calculated by receiver operating characteristic (ROC) curve analysis. Results:In 300 women with breast cancer treated with POC, QOL was significantly reduced (P?

SUBMITTER: Takada K 

PROVIDER: S-EPMC6354182 | biostudies-other | 2019 Feb

REPOSITORIES: biostudies-other

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Prognostic value of quality-of-life scores in patients with breast cancer undergoing preoperative chemotherapy.

Takada K K   Kashiwagi S S   Fukui Y Y   Goto W W   Asano Y Y   Morisaki T T   Takashima T T   Hirakawa K K   Ohira M M  

BJS open 20181126 1


<h4>Background</h4>Recently, evaluation of quality of life (QOL) has been recognized as a significant outcome measure in the treatment of several cancers. In this study, the Anti-Cancer Drugs-Breast (ACD-B) QOL score was used to assess disease-specific survival in women with breast cancer undergoing preoperative chemotherapy (POC).<h4>Methods</h4>QOL-ACD-B scores were evaluated before and after POC. The cut-off value of QOL-ACD-B contributing to events such as relapse or death was calculated by  ...[more]

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