Dataset Information

Comparison of Mitochondrial Respiration in M. triceps brachii and M. vastus lateralis Between Elite Cross-Country Skiers and Physically Active Controls.

ABSTRACT: Rationale:The main purposes of this study were to compare mitochondrial respiration in M. triceps brachii and M. vastus lateralis between elite cross-country (XC) skiers and physically active controls (CON), and to explore the associations between mitochondrial respiration in these muscles and peak oxygen uptake ( V˙ O2peak) in arm- and leg-dominant exercise modes. Methods:Thirteen male elite XC skiers (age: 25 ± 4; peak oxygen uptake ( V˙ O2peak): 75.5 ± 4.2 mL⋅kg-1⋅min-1) and twelve CON (age: 26 ± 3; V˙ O2peak: 57.2 ± 6.4 mL⋅kg-1⋅min-1) had microbiopsies taken from M. vastus lateralis and M. triceps brachii, which were analyzed for various measures of mitochondrial respiration using high-resolution respirometry. Thereafter, all participants tested V˙ O2peak in both running (RUN) and upper body poling (UBP). Results:XC skiers had generally higher mitochondrial respiration in M. triceps brachii compared to CON (P < 0.001), whereas no significant group-differences in mitochondrial respiration in M. vastus lateralis were revealed. XC skiers had higher mitochondrial respiration in M. triceps brachii compared to M. vastus lateralis (P = 0.005-0.058), whereas in CON, most mitochondrial respiration measures were higher in M. vastus lateralis than in M. triceps brachii (P < 0.01). When all athletes were pooled, there was a strong positive correlation between V˙ O2peak in UBP and mitochondrial respiration in M. triceps brachii on several measures (P < 0.01), whereas no correlation was found for RUN. Conclusion:The higher mitochondrial respiration found in M. triceps brachii compared to M. vastus lateralis among our elite XC skiers demonstrates the potential for the arm muscles to adapt to aerobic endurance training. The opposite pattern found in CON, clearly showed lower mitochondrial respiration in M. triceps brachii compared to XC skiers, whereas respiration in M. vastus lateralis did not differ between groups. The strong positive correlation between mitochondrial respiration in M. triceps brachii and V˙ O2peak in UBP indicate that arm muscles' respiratory function may be a limiting factor for V˙ O2peak in arm-dominant exercise modes.

SUBMITTER: Berg J

PROVIDER: S-EPMC6461012 | biostudies-other | 2019

REPOSITORIES: biostudies-other

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Comparison of Mitochondrial Respiration in M. triceps brachii and M. vastus lateralis Between Elite Cross-Country Skiers and Physically Active Controls.

Berg Jonathan J Undebakke Vidar V Rasch-Halvorsen Øystein Ø Aakerøy Lars L Sandbakk Øyvind Ø Tjønna Arnt Erik AE

Frontiers in physiology 20190405

<h4>Rationale</h4>The main purposes of this study were to compare mitochondrial respiration in M. triceps brachii and M. vastus lateralis between elite cross-country (XC) skiers and physically active controls (CON), and to explore the associations between mitochondrial respiration in these muscles and peak oxygen uptake ( V ˙ O<sub>2peak</sub>) in arm- and leg-dominant exercise modes.<h4>Methods</h4>Thirteen male elite XC skiers (age: 25 ± 4; peak oxygen uptake ( V ˙ O<sub>2peak</sub>): 75.5 ± ...[more]

PMID: 31024334

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Project description:Single-leg squat (SLS) is a functional test visually rated by clinicians for assessing lower limb function as a preventive injury strategy. SLS clinical rating is a qualitative evaluation and it does not count objective outcomes as kinematics data and surface electromyography (sEMG) assessment. Based on the SLS rating, the aims of this study were (i) to determine the clinical rating agreement among six raters and (ii) to assess kinematic and sEMG predictors of good SLS performance in physically and non-physically active individuals.Seventy-two healthy adults, divided in physically active and non-physically active groups, performed three SLSs on their dominant leg. Clinical ratings, kinematic data and sEMG were acquired. By using a validated clinical scale, six expert clinicians rated each SLS watching a video at three different time points. Intra and inter-rater agreement of clinical ratings were undertaken and a binary logistic regression analysis was used to determine kinematic and sEMG as predictors of SLS performance.The weighted kappa coefficient for intra-rater reliability within each rater ranged between moderate and almost perfect agreement (0.55-0.85) whereas the weighted kappa coefficient for inter-rater reliability among raters was fair (0.34, time point 0; 0.31, time point 1; 0.30, time point 2). SLS analyses of physically active compared to non-physically active group showed a statistically significant difference in knee flexion and hip flexion (p = 0.041 and p = 0.023 respectively) and no difference in clinical ratings (p = 0.081). Greater knee flexion can predict the good SLS performance taking into account the belonging group (p = 0.019).Physically active individuals seemed to be at less risk to perform a non-good SLS and they had greater knee and hip flexions kinematics than non-physically active individuals. Knee flexion can predict the SLS performance quality therefore a greater knee flexion might also be considered a protective element from injuries.ClinicalTrials.gov identifier (trial has been registred retrospectively: NCT03203083. Date registration: June 21, 2017.

Dataset Information

Comparison of Mitochondrial Respiration in M. triceps brachii and M. vastus lateralis Between Elite Cross-Country Skiers and Physically Active Controls.

Publications

Comparison of Mitochondrial Respiration in M. triceps brachii and M. vastus lateralis Between Elite Cross-Country Skiers and Physically Active Controls.

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