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Microstructure arrays of DNA using topographic control.

ABSTRACT: DNA is a common biomaterial in nature as well as a good building block for producing useful structures, due to its fine feature size and liquid crystalline phase. Here, we demonstrate that a combination of shear-induced flow and microposts can be used to create various kinds of interesting microstructure DNA arrays. Our facile method provides a platform for forming multi-scale hierarchical orientations of soft- and biomaterials, using a process of simple shearing and controlled evaporation on a patterned substrate. This approach enables potential patterning applications using DNA or other anisotropic biomaterials based on their unique structural characteristics.

SUBMITTER: Cha YJ

PROVIDER: S-EPMC6555807 | biostudies-other | 2019 Jun

REPOSITORIES: biostudies-other

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Microstructure arrays of DNA using topographic control.

Cha Yun Jeong YJ Park Soon Mo SM You Ra R Kim Hyoungsoo H Yoon Dong Ki DK

Nature communications 20190607 1

DNA is a common biomaterial in nature as well as a good building block for producing useful structures, due to its fine feature size and liquid crystalline phase. Here, we demonstrate that a combination of shear-induced flow and microposts can be used to create various kinds of interesting microstructure DNA arrays. Our facile method provides a platform for forming multi-scale hierarchical orientations of soft- and biomaterials, using a process of simple shearing and controlled evaporation on a ...[more]

PMID: 31175307

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