Ontology highlight
ABSTRACT:
SUBMITTER: Kaltschmidt C
PROVIDER: S-EPMC6563002 | biostudies-other | 2019 May
REPOSITORIES: biostudies-other
Kaltschmidt Christian C Banz-Jansen Constanze C Benhidjeb Tahar T Beshay Morris M Förster Christine C Greiner Johannes J Hamelmann Eckard E Jorch Norbert N Mertzlufft Fritz F Pfitzenmaier Jesco J Simon Matthias M Schulte Am Esch Jan J Vordemvenne Thomas T Wähnert Dirk D Weissinger Florian F Wilkens Ludwig L Kaltschmidt Barbara B
Cancers 20190511 5
Cancer stem cells (CSCs) account for tumor initiation, invasiveness, metastasis, and recurrence in a broad range of human cancers. Although being a key player in cancer development and progression by stimulating proliferation and metastasis and preventing apoptosis, the role of the transcription factor NF-κB in cancer stem cells is still underestimated. In the present review, we will evaluate the role of NF-κB in CSCs of glioblastoma multiforme, ovarian cancer, multiple myeloma, lung cancer, col ...[more]