Ontology highlight
ABSTRACT:
SUBMITTER: Miyazaki A
PROVIDER: S-EPMC6791893 | biostudies-other | 2019 Oct
REPOSITORIES: biostudies-other
Miyazaki Aya A Sugimoto Asuna A Yoshizaki Keigo K Kawarabayashi Keita K Iwata Kokoro K Kurogoushi Rika R Kitamura Takamasa T Otsuka Kunihiro K Hasegawa Tomokazu T Akazawa Yuki Y Fukumoto Satoshi S Ishimaru Naozumi N Iwamoto Tsutomu T
Scientific reports 20191014 1
Signal transmission from the mechanical forces to the various intracellular activities is a fundamental process during tissue development. Despite their critical role, the mechanism of mechanical forces in the biological process is poorly understood. In this study, we demonstrated that in the response to hydrostatic pressure (HP), the piezo type mechanosensitive ion channel component 1 (PIEZO1) is a primary mechanosensing receptor for odontoblast differentiation through coordination of the WNT e ...[more]