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NCI Genome-Wide Association Study of Renal Cell Carcinoma

ABSTRACT:

The National Cancer Institute (NCI) genome-wide association study (GWAS) of renal cell carcinoma (RCC) was conducted to investigate common genetic variants associated with RCC risk. The GWAS includes 1,453 RCC cases and 3,531 controls of European background from 4 studies (3 cohort, 1 case-control), scanned using the Illumina InfiniumHumanHap 550, 610 and 660W chips. This project was supported by the Intramural Research Program of the National Institutes of Health and NCI.

Data from this GWAS were pooled with those from another GWAS of RCC (2,639 cases and 5,392 controls) conducted in Europe by the International Agency for Research on Cancer and the Centre National de Gènotypage. Findings from this collaboration are described in an upcoming report (Purdue et al. Nature Genetics 2011;43(1):60-65; PMID: 21131975).

Only data from the NCI scan are included in this dbGaP submission.

PROVIDER: phs000351 | dbGaP |

SECONDARY ACCESSION(S): PRJNA75815PRJNA75813

REPOSITORIES: dbGaP

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Dataset's files

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			Action	DRS
	GapExchange_phs000351.v1.p1.xml	Xml
	dbGaPEx2.1.5.xsd	Other
	phs000351.v1-Documents.zip	Other
	Study_Report.phs000351.CGEMS_RenalCellCarcinoma.v1.p1.MULTI.pdf	Pdf
	manifest_phs000351.CGEMS_RenalCellCarcinoma.v1.p1.c1.CADM.pdf	Pdf

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National Cancer Institute Genome-Wide Association Study of Renal Cell Carcinoma

Project description:The National Cancer Institute (NCI) genome-wide association study (GWAS) of renal cell carcinoma (RCC) was conducted to investigate common genetic variants associated with RCC risk. The GWAS includes 1,453 RCC cases and 3,531 controls of European background from 4 studies (3 cohort, 1 case-control), scanned using the Illumina InfiniumHumanHap 550, 610 and 660W chips. This project was supported by the Intramural Research Program of the National Institutes of Health and NCI. Data from this GWAS were pooled with those from another GWAS of RCC (2,639 cases and 5,392 controls) conducted in Europe by the International Agency for Research on Cancer and the Centre National de Gènotypage. Findings from this collaboration are described in an upcoming report (Purdue et al. Nature Genetics 2011;43(1):60-65; PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/21131975" target="_blank">21131975</a>). Only data from the NCI scan are included in this dbGaP submission.

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