Genomic

Dataset Information

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Orofacial Pain: Prospective Evaluation and Risk Assessment (OPPERA)


ABSTRACT:

The OPPERA project has two sub-studies investigating effects of genetic, physiological, psychological and clinical factors on the risk of developing painful temporomandibular disorder (TMD).

  1. OPPERA I baseline case-control study of chronic TMJD (dbGaP study accession phs000762). This sub-study uses a case-control study design to investigate characteristics associated with chronic TMD. The parent OPPERA phenotype file contains an indicator variable (PHASE1CASECONTROL) identifying participants in this sub-study. Data users should use the relevant case-classification variable (CHRNONICTMDCASE) and apply statistical methods appropriate for case-control studies when analyzing TMJD in this sub-study.
  2. OPPERA I prospective cohort for first onset of TMJD (dbGaP study accession phs000850). This sub-study uses a prospective cohort study design to investigate characteristics that predict risk of developing first-onset TMD. The parent OPPERA phenotype file contains an indicator variable (PROSPECTIVECOHORT) identifying participants in this sub-study. Data users should use the relevant case-classification variable (INCIDENTCASE) and the relevant time-in-study variable (FOLLOWUPYEARS) when analyzing TMJD in this sub-study. It is recommended that data users apply statistical methods appropriate for cohort studies of a dynamic population (for example, Cox regression models, where INCIDENTCASE is the censoring variable and FOLLOWUPYEARS is time in study).

PROVIDER: phs000761 | dbGaP |

SECONDARY ACCESSION(S): PRJNA253230PRJNA253229

REPOSITORIES: dbGaP

Dataset's files

Source:
Action DRS
GapExchange_phs000761.v1.p1.xml Xml
dbGaPEx2.1.5.xsd Other
phs000761.v1-Documents.zip Other
phs000762.v1-Documents.zip Other
phs000850.v1-Documents.zip Other
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