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OFCCR SNP-CpG

ABSTRACT:

We profiled the methylation landscape of ~2100 DNA samples (~1100 cases of colorectal cancer and ~1000 controls) from the Ontario Familial Colon Cancer Registry (OFCCR) using the HumanMethylation450 array from Illumina. DNA was extracted from lymphocyte pellets, except for 99 samples for which DNA was extracted from lymphoblastoid cell lines. Samples were genotyped on the Affymetrix Human Mapping 100k and 500k arrays. The aim the study was to evaluate the interplay between genetic variation and methylation, including long-range epigenetic regulation.

PROVIDER: phs000779 | dbGaP |

SECONDARY ACCESSION(S): PRJNA255928PRJNA255927

REPOSITORIES: dbGaP

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	GapExchange_phs000779.v1.p1.xml	Xml
	dbGaPEx2.1.5.xsd	Other
	Study_Report.phs000779.OFCCR_SNP_CpG.v1.p1.MULTI.pdf	Pdf
	manifest_phs000779.OFCCR_SNP_CpG.v1.p1.c1.DS-CA-IRB.pdf	Pdf
	datadict_v2.xsl	Other

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