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Irinotecan, Cisplatin, and Bevacizumab in Treating Patients With Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

ABSTRACT: This phase II trial is studying how well giving irinotecan and cisplatin together with bevacizumab works in treating patients with unresectable or metastatic gastric (stomach) or gastroesophageal junction adenocarcinoma (cancer). Drugs used in chemotherapy, such as irinotecan and cisplatin, work in different ways to stop tumor cells from dividing so they stop growing or die. Monoclonal antibodies such as bevacizumab can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells. Giving chemotherapy together with a monoclonal antibody may kill more tumor cells.

DISEASE(S): Diffuse Adenocarcinoma Of The Stomach,Adenocarcinoma,Recurrent Gastric Cancer,Stage Iv Gastric Cancer,Intestinal Adenocarcinoma Of The Stomach,Stage Iiib Gastric Cancer,Adenocarcinoma Of The Gastroesophageal Junction,Stomach Neoplasms,Stage Iiic Gastric Cancer,Mixed Adenocarcinoma Of The Stomach,Stage Iiia Gastric Cancer

PROVIDER: 2010923 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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