MDX-010 in Treating Patients With Recurrent or Refractory Lymphoma

ABSTRACT: Biological therapies, such as MDX-010, work in different ways to stimulate the immune system and stop cancer cells from growing. This phase I/II trial is studying the side effects and best dose of MDX-010 and to see how well it works in treating patients with recurrent or refractory B-cell non-Hodgkin’s lymphoma.

DISEASE(S): Extranodal Marginal Zone B-cell Lymphoma Of Mucosa-associated Lymphoid Tissue,Lymphoma, Large B-cell, Diffuse,Adult Grade Iii Lymphomatoid Granulomatosis,Lymphoma, Large-cell, Immunoblastic,Hodgkin Disease,Leukemia,Recurrent Adult Hodgkin Lymphoma,Waldenström Macroglobulinemia,Recurrent Adult Lymphoblastic Lymphoma,Small Intestine Lymphoma,Recurrent Grade 1 Follicular Lymphoma,Refractory Hairy Cell Leukemia,Testicular Lymphoma,Splenic Marginal Zone Lymphoma,Leukemia, Hairy Cell,Lymphoma, Mantle-cell,Recurrent Adult Immunoblastic Large Cell Lymphoma,Recurrent Adult Burkitt Lymphoma,Lymphomatoid Granulomatosis,Lymphoma, Extranodal Nk-t-cell,Plasmablastic Lymphoma,Precursor Cell Lymphoblastic Leukemia-lymphoma,Lymphoma, B-cell, Marginal Zone,Burkitt Lymphoma,B-cell Chronic Lymphocytic Leukemia,Lymphoma,Recurrent Adult Diffuse Small Cleaved Cell Lymphoma,Nodal Marginal Zone B-cell Lymphoma,Recurrent Adult Diffuse Mixed Cell Lymphoma,Recurrent Marginal Zone Lymphoma,Recurrent Grade 2 Follicular Lymphoma,Lymphoma, Follicular,Waldenstrom Macroglobulinemia,Recurrent Adult Grade Iii Lymphomatoid Granulomatosis,Lymphoma, Non-hodgkin,Recurrent Adult Diffuse Large Cell Lymphoma,Intraocular Lymphoma,Leukemia, Lymphocytic, Chronic, B-cell,Lymphoma, B-cell,Cutaneous B-cell Non-hodgkin Lymphoma,Recurrent Mantle Cell Lymphoma

PROVIDER: 2011229 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR