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Denileukin Diftitox Followed by Vaccine Therapy in Treating Patients With Metastatic Cancer

ABSTRACT: RATIONALE: Combinations of biological substances in denileukin diftitox may be able to carry cancer-killing substances directly to the cancer cells. Vaccines made from a gene-modified virus and a person’s white blood cells may help the body build an effective immune response to kill cancer cells. Giving denileukin diftitox together with vaccine therapy may kill more cancer cells. PURPOSE: This phase I trial is studying the side effects of giving denileukin diftitox together with vaccine therapy in treating patients with metastatic cancer that expresses carcinoembryonic antigen.

DISEASE(S): Lung Cancer,Colorectal Cancer,Pancreatic Cancer,Breast Neoplasms,Pancreatic Neoplasms,Breast Cancer,Lung Neoplasms,Unspecified Adult Solid Tumor, Protocol Specific

PROVIDER: 2014133 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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