Clinical

Dataset Information

0

A Study of EZN-2208 Administered With or Without Cetuximab in Patients With Metastatic Colorectal Carcinoma


ABSTRACT: This is a Phase 2, multicenter, multiple-arm, open-label study to evaluate the efficacy, safety, and tolerability of EZN-2208. EZN-2208 will be administered as a single agent in patients with K-RAS mutations in the tumors. Patients with wild type K-RAS in tumors will be randomized to EZN-2208 + cetuximab or to standard of care (Camptosar + cetuximab), patients must have failed regimens containing irinotecan (Camptosar, CPT-11), oxaliplatin (Eloxatin), and fluoropyrimidine. After discontinuation of study treatment, patients will receive care as considered appropriate by the investigator. Patients will continue to be followed for disease progression, subsequent anticancer therapy, and survival.

DISEASE(S): Metastatic Colorectal Cancer,Mestatic Colorectal Cancer,Colorectal Cancer Metastatic,Colorectal Neoplasms

PROVIDER: 2074580 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

Similar Datasets

2014-09-18 | E-GEOD-61495 | biostudies-arrayexpress
2014-09-18 | GSE61495 | GEO
2014-04-01 | E-GEOD-56386 | biostudies-arrayexpress
2020-05-06 | GSE108277 | GEO
2017-03-02 | GSE63916 | GEO
2012-07-27 | E-MTAB-991 | biostudies-arrayexpress
2012-07-27 | E-MTAB-992 | biostudies-arrayexpress
2012-07-13 | E-GEOD-23428 | biostudies-arrayexpress
2014-04-01 | GSE56386 | GEO
2020-11-02 | GSE141352 | GEO