Gemcitabine Hydrochloride, Oxaliplatin, and Erlotinib Hydrochloride in Treating Patients With Advanced Biliary Tract Cancer, Pancreatic Cancer, Duodenal Cancer, or Ampullary Cancer
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ABSTRACT: RATIONALE: Drugs used in chemotherapy, such as gemcitabine hydrochloride and oxaliplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Erlotinib hydrochloride may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving gemcitabine hydrochloride and oxaliplatin together with erlotinib hydrochloride may kill more tumor cells.
PURPOSE: This phase I trial is studying the side effects and best dose of erlotinib hydrochloride when given together with gemcitabine hydrochloride and oxaliplatin in treating patients with advanced biliary tract cancer, pancreatic cancer, duodenal cancer, or ampullary cancer.
DISEASE(S): Adenocarcinoma,Periampullary Adenocarcinoma,Biliary Tract Neoplasms,Liver Cancer,Small Intestine Cancer,Pancreatic Cancer,Gallbladder Cancer,Extrahepatic Bile Duct Cancer,Liver Neoplasms,Gallbladder Neoplasms,Bile Duct Neoplasms,Adenocarcinoma Of The Gallbladder,Pancreatic Neoplasms,Intestinal Neoplasms,Cholangiocarcinoma
PROVIDER: 2078817 | ecrin-mdr-crc |
REPOSITORIES: ECRIN MDR
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