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Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT

ABSTRACT: The objective of this study is to evaluate the efficacy of using a reduced-intensity condition (RIC) regimen with umbilical cord blood transplant (UCBT), double cord UCBT, matched unrelated donor (MUD) bone marrow transplant (BMT) or peripheral blood stem cell transplant (PBSCT) in patients with non-malignant disorders that are amenable to treatment with hematopoietic stem cell transplant (HSCT). After transplant, subjects will be followed for late effects and for ongoing graft success.

DISEASE(S): Crohn’s Disease,Inflammatory Conditions,Systemic Juvenile Idiopathic Arthritis (sjia),Anemia,Congenital Bone Marrow Failure Syndromes,Metabolic Diseases,Leukodystrophies,Arthritis,Krabbe Disease,Inherited Metabolic Disorders (imd),Primary Immunodeficiency Diseases,Arthritis, Juvenile,Bone Marrow Failure Disorders,Pancytopenia,Hereditary Anemias,Primary Immunodeficiency (pid)

PROVIDER: 2153130 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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