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M6620 and Irinotecan Hydrochloride in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

ABSTRACT: This phase I trial studies the side effects and best dose of M6620 and irinotecan hydrochloride in treating patients with solid tumors that have spread to other places in the body (metastatic) or cannot be removed by surgery (unresectable). M6620 and irinotecan hydrochloride may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

DISEASE(S): Carcinoma,Metastatic Malignant Solid Neoplasm,Unresectable Malignant Solid Neoplasm,Metastatic Colorectal Carcinoma,Lung Neoplasms,Neoplasms,Stage Iii Pancreatic Cancer Ajcc V8,Carcinoma, Small Cell,Colorectal Neoplasms,Unresectable Lung Small Cell Carcinoma,Pancreatic Neoplasms,Stage Iv Pancreatic Cancer Ajcc V8,Unresectable Colorectal Carcinoma,Stage Iii Lung Cancer Ajcc V8,Stage Iv Colorectal Cancer Ajcc V8,Small Cell Lung Carcinoma,Refractory Malignant Solid Neoplasm,Unresectable Pancreatic Carcinoma,Metastatic Pancreatic Carcinoma,Metastatic Lung Small Cell Carcinoma,Stage Iii Colorectal Cancer Ajcc V8,Stage Iv Lung Cancer Ajcc V8,Refractory Lung Small Cell Carcinoma,Refractory Pancreatic Carcinoma,Refractory Colorectal Carcinoma

PROVIDER: 2201648 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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