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A Study of Autogene Cevumeran (RO7198457) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors

ABSTRACT: This is a Phase 1a/1b, open-label, multicenter, global, dose-escalation study designed to evaluate the safety, tolerability, immune response, and pharmacokinetics of autogene cevumeran (RO7198457) as a single agent and in combination with atezolizumab (MPDL3280A, an engineered anti-programmed death-ligand 1 [anti-PD-L1] antibody).

DISEASE(S): Kidney Neoplasms,Neoplasm Metastasis,Other Solid Cancers,Triple Negative Breast Neoplasms,Melanoma,Non-small Cell Lung Cancer,Colorectal Cancer,Renal Cancer,Bladder Cancer,Triple Negative Breast Cancer,Head And Neck Cancer

PROVIDER: 2254883 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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