Browse
Submit Data
Databases
API
Help

Dataset Information

32 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Mechanical Bowel Preparation With or Without Oral Antibiotics for Colorectal Cancer Surgery

ABSTRACT: Investigation of the role of adding oral antibiotics to preoperative mechanical bowel preparation before colorectal surgery for cancer.

DISEASE(S): Surgical Site Infection,Bowel Cancer,Antibiotic,Colorectal Cancer,Colorectal Neoplasms,Surgical Wound Infection

PROVIDER: 2275878 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

ACCESS DATA

Json Xml

Similar Datasets

Mechanical Bowel Preparation and Oral Antibiotics Before Colon Cancer Surgery

Project description:This study aims to demonstrate that a preoperative combination of mechanical bowel preparation and oral antibiotics, before elective laparoscopic colon cancer surgery, is associated with a reduction of postoperative surgical site infection rate, as compared to mechanical bowel preparation alone, oral antibiotics alone, or no colonic preparation. Our Hypothesis is that a preoperative colonic preparation including a combination of mechanical bowel preparation and oral antibiotics before elective laparoscopic colon cancer surgery is associated with a reduced rate of 30-day postoperative surgical site infection, as compared to mechanical bowel preparation alone, oral antibiotics alone, or no colonic preparation.

| 2269131 | ecrin-mdr-crc

Mechanical Bowel Preparation and Oral Antibiotics Before Rectal Cancer Surgery

Project description:This study aims to demonstrate that a preoperative combination of mechanical bowel preparation and oral antibiotics, before elective laparoscopic rectal cancer surgery, is associated with a reduction of postoperative surgical site infection rate, as compared to mechanical bowel preparation alone Our hypothesis is that a preoperative colonic preparation including a combination of mechanical bowel preparation and oral antibiotics before elective laparoscopic rectal cancer surgery is associated with a reduced rate of 30-day postoperative surgical site infection, as compared to mechanical bowel preparation alone

| 2270348 | ecrin-mdr-crc

Mechanical Bowel Preparation and Oral Antibiotics Versus Mechanical Bowel Preparation Only Prior Rectal Surgery

Project description:MOBILE2 is a randomized controlled trial comparing mechanical and oral antibiotic bowel preparation to mechanical bowel preparation only in patients undergoing anterior rectal resection with primary anastomosis. Primary endpoint is Comprehensive Complication Index within 30 days from surgery.

| 2331037 | ecrin-mdr-crc

Prophylatic Effect Preoperative Antibiotics With Mechanical Bowel Preparation in SSIs

Project description:Surgical site infection (SSI) is a major postoperative complication after abdominal surgery especially in colorectal field, which significantly increases length of stay (LOS), readmission incidence and expense. Therefore, identification of the effective method to reduce SSI incidence is critically important. Combination of oral antibiotics and mechanical bowel preparation was reported with lower SSIs and LOS in some retrospecitve data analysis, however a prospective randmized controlled trial was absent. Herein, the current randomized controlled trial comparing MBP+OA with MBP alone in postoperative complications in order to guide clinical practise was conducted.

| 2298394 | ecrin-mdr-crc

infectious surgical site complications after oral antibiotic bowel preparation for minimally-invasive rectal cancer surgery

Project description:Interventions: Drug : 1. experimental group (A) - mechanical bowel preparation (PEG) + IV antibiotics 2. control group (B) - mechanical bowel preparation (PEG) + IV antibiotics + oral antibiotics (rifaximin + metronidazole) 3. pre-operative preparation 3.1. mechanical bowel preparation - PEG prefered - water only permitted on the day before operation 3.2. oral antibiotics - 14, 16, 22 hour the day before surgery - 400mg rifaximin + 500mg metronidazole 3.3. IV antibiotics - 2nd generation cephalosporin - venous injection within 30 minutes before surgery - additional dose is at the discretion of the operators Primary outcome(s): surgical site infection rate during first 30 days Primary Purpose : Prevention, Intervention Model : Factorial, Blinding/Masking : Open, Allocation : RCT

| 2512754 | ecrin-mdr-crc

Preoperative mechanical bowel preparation in patients with colon cancer

Project description:Interventions: Standard therapy group 2L of Niflex as mechanical bowel preparation trial therapy group no mechanical bowel preparation Primary outcome(s): incisional surgical site infection (SSI) Study Design: Parallel Randomized

| 2628847 | ecrin-mdr-crc

Short-term Outcomes of Full Bowel Preparation (MBP+OA) for Colon Cancer Resections Versus no Bowel Preparation

Project description:The purpose of the study is to determine if short-term outcomes of colon resections after full bowel preparation (mechanical bowel preparation plus oral antibiotics) are superior to colon resections with no bowel preparation.

| 2748859 | ecrin-mdr-crc

Short-term Outcomes of Full Bowel Preparation (MBP+OA) for Rectal Resections for Cancer Versus MBP Alone

Project description:The purpose of the study is to determine if short-term outcomes of rectal resections after full bowel preparation (mechanical bowel preparation plus oral antibiotics) are superior to rectal resections with only mechanical bowel preparation.

| 2354896 | ecrin-mdr-crc

Rectal Cancer Surgery Without Mechanical Bowel Preparation

Project description:The aim of this controlled multicentric study is to assess rectal cancer surgery with sphincter preservation without pre operative mechanical bowel preparation

| 2046127 | ecrin-mdr-crc

Mechanical Bowel Preparation Versus no Bowel Preparation for Esophageal Cancer Surgery

Project description:The study type was designed as a prospective multicenter randomized controlled study. The patients will be divided into intervention group (126 cases) and control group, 281 patients were needed for each group and 562 patients would be needed totally to show this difference. The intervention group will not implement mechanical bowel preparation(MBP) before surgery; the control group will receive routine preoperative MBP for oral administration of compound polyethylene glycol electrolyte powder and fasting water. Perioperative complications, intestinal recovery speed and quality of life will be investigated between the two groups.

| 2747027 | ecrin-mdr-crc

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data