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The Effects of RFA in Combination With Second-line Chemotherapy and Bevacizumab on Unresectable CRLM

ABSTRACT: Basing on the strong evidence from former researches, patients with CRLM can benefit from the treatment of bevacizumab combined with sencond-line chemotherapy. Recently, although with the popularization of RFA, the role that RFA plays in the long term survival of patients with metastatic colorectal cancer (CRC) is still confused. In this designed, randomized, controlled, prospective, and open clinical trial, the effectiveness of RFA combined with second-line chemotherapy + bevacizumab on unresectable CRLM is going to be evaluated compared with that of second-line chemotherapy + bevacizumab. After screened by inclusion and exclusion criteria, the eligible subjects will be randomly allocated into the experimental group-with the treatment of RFA + second-line chemotherapy + bevacizumab and control group-with the treatment of second-line chemotherapy + bevacizumab equally.

DISEASE(S): Colorectal Neoplasms Malignant,Colorectal Neoplasms,Neoplasms

PROVIDER: 2285301 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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