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A Study of ASP1951 in Subjects With Advanced Solid Tumors

ABSTRACT: The primary purpose of this study is to evaluate the tolerability and safety profile of ASP1951 when administered as a single agent and in combination with pembrolizumab in participants with locally advanced (unresectable) or metastatic solid tumors; characterize the pharmacokinetic profile of ASP1951 when administered as a single agent and in combination with pembrolizumab; and determine the recommended phase 2 dose (RP2D) of ASP1951 and/or maximum tolerated dose (MTD) when administered as a single agent and in combination with pembrolizumab. This study will also evaluate the anti-tumor effect of ASP1951 when administered as a single agent and in combination with pembrolizumab.

DISEASE(S): Cervical Cancer,Melanoma,Advanced Solid Tumors,Colorectal Cancer,Neoplasms

PROVIDER: 2293965 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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