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Pediatric Reporting of Adult-Onset Genomic Results

ABSTRACT: The Investigators will conduct a longitudinal, mixed-methods cohort study to assess primary and secondary psychosocial outcomes among 705 MyCode pediatric participants and their parents, and health behaviors of parents whose children receive an adult- or pediatric-onset genomic result. Data will be gathered via quantitative surveys using validated measures of distress, family functioning, quality of life, body image, perceived cancer/heart disease risk, genetic counseling satisfaction, genomics knowledge, and adjustment to genetic information; qualitative interviews with adolescents and parents; and electronic health records review of parents’ cascade testing uptake and initiation of risk reduction behaviors. The investigators will also conduct empirical and theoretical legal research to examine the loss of chance doctrine and its applicability to genomic research.

DISEASE(S): Hypercholesterolemia,Lynch Syndrome,Hyperlipoproteinemia Type Ii,Hereditary Breast And Ovarian Cancer Syndrome,Colorectal Neoplasms, Hereditary Nonpolyposis,Familial Hypercholesterolemia

PROVIDER: 2296574 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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