Clinical

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TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers


ABSTRACT: TTX-080-001 is a Phase 1, open label, dose escalation and dose expansion clinical study to determine the safety, tolerability, and recommended Phase 2 dose of TTX-080 monotherapy (HLA-G inhibitor) and in combination with either pembrolizumab (PD-1 inhibitor) or cetuximab (EGFR inhibitor) in patients with advanced refractory / resistant solid malignancies. The study is enrolling in the dose expansion arms.

DISEASE(S): Endometrial Cancer,Lung Cancer,Cervical Cancer,Melanoma,Colorectal Cancer,Bladder Cancer,Breast Cancer,Ovarian Cancer,Gastric Cancer,Advanced Solid Tumor,Prostate Cancer,Head And Neck Cancer,Cancer

PROVIDER: 2346653 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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