Comparing two optical technologies when screening for bowel cancer: a trial from several UK hospitals

ABSTRACT: Background and study aims The UK bowel cancer screening program has been set up to help detect bowel cancer offering colonoscopy to patients having a positive faecal occult blood test, which is a test that detects blood in someone’s stools. Colonoscopy is the gold standard tool for finding bowel cancer and polyps (type of growth that sticks up out of tissue) or adenomas (non-cancerous tumours). High quality colonoscopy largely depends on quality procedures and skills of the operator, which can vary extensively. Olympus and Pentax are two frequently used colonoscopy technologies in the UK. Although both use the same principle of video endoscopy, each type of instrument has different features that allow the operators the best options for manoeuvres and correctness, allowing for more certainty in diagnosis and better patient comfort. This study aims to compare these two optical technologies (standard definition Olympus Lucera (SD-OL) with Scope Guide against the high definition Pentax HiLine (HD-PHL)) when screening for bowel cancer in a randomised controlled trial from several UK hospitals. Who can participate? Adults who tested positive on a faecal occult blood test and were scheduled to undergo a first colonoscopy as part of National bowel cancer screening program. What does the study involve? Patients will be allocated randomly to either of the optical technologies under comparison (SD-OL vs HD-PHL). Then patients’ notes will be reviewed by the research team to record the frequency of detecting polyps and adenomas as well as procedural information, such as length of procedure, patient comfort, and type and dosage of medication used to make patients drowse or sleepy.

DISEASE(S): Colorectal Cancer And Polyps

PROVIDER: 2421292 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR