Clinical

Dataset Information

0

Exercise Prehabilitation in High Risk Cancer Surgery: A Feasibility Study


ABSTRACT: Interventions: Eligible participants will be prescribed an exercise program for a period of six weeks or up until surgery (whichever is earlier). Exercise prescriptions will be individualized to a participant’s prior aerobic fitness, medical comorbidities, response to any prior treatment and any immediate negative treatment effects of prior treatment (such as ongoing neuropathy and/or cancer cachexia) as per the ACSM Guidelines for exercise prescription. Exercise programs will be conducted one-on-one either in person in a hospital-based gym or unsupervised within the home environment based on the patient’s preference and ability to travel to the hospital. Exercise programs will be moderate to vigorous intensity as rated by the Borg RPE rating scale and prescribed in conjunction with cardiopulmonary exercise testing results. Exercise programs will include at least 3x30min aerobic exercise (walking/cycling/swimming) and 2x30min resistance sessions (upper and lower body strengthening exercises e.g. sit to stand, step ups, shoulder press) per week based on whether participants are meeting the ACSM exercise prescription guidelines at baseline. Participants will also be provided with a respiratory education session including information regarding breathing exercises to complete in the lead up to surgery. Given the complexity of this patient sample exercise prescription will also be adapted upon previous musculoskeletal injuries/issues (e.g. previous total joint replacements) and patients exercise preferences, to increase adherence with six-week program. Exercise programs will be progressed by a qualified physiotherapist and/or exercise physiologist based on participant’s response to exercise and compliance with the exercise program. The 30 min respiratory ed Primary outcome(s): Feasibility of delivering a six week individualized Exercise Prehabilitation Program amongst high risk surgical patients presenting for major cancer surgery. Feasibility of the program will be defined as: •Percentage of patients consenting to the exercise program = >70% consent rate •>70% adherence to exercise prescribed, as determined by participant exercise diaries •>85% retention in the study (Measures of non-compliance including dropout rates and reasons for drop out) •Intervention acceptability to patients •Cost of resources to run the study [Prior to surgery] Study Design: Purpose: Treatment; Allocation: Non-randomised trial; Type of endpoint: Safety/efficacy

DISEASE(S): Major Abdominal Cancer Surgery,Cancer-bowel-small Bowel (duodenum And Ileum),Cancer-stomach,Physical Medicine / Rehabilitation-other Physical Medicine / Rehabilitation,Cancer-bowel-back Passage (rectum) Or Large Bowel (colon),Cancer-oesophageal (gullet)

PROVIDER: 2470295 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

Similar Datasets

2024-10-17 | PXD047623 | Pride
2007-06-07 | E-MEXP-740 | biostudies-arrayexpress
| 73480 | ecrin-mdr-crc
2022-12-31 | E-MTAB-11166 | biostudies-arrayexpress
2013-06-29 | E-GEOD-48405 | biostudies-arrayexpress
2022-11-04 | PXD025956 | Pride
2022-03-14 | GSE198266 | GEO
2007-07-16 | GSE8479 | GEO
| 2472945 | ecrin-mdr-crc
| 73485 | ecrin-mdr-crc