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RECIST 1.1 and iRECIST evaluation for patients with deficient MMR and/or MSI Metastatic Colorectal Cancer treated with nivolumab and ipilimumab.

ABSTRACT: Primary objectives: Comparison of DCR at 12 weeks by RECIST and iRECIST (Central Review) Evaluation of RECIST and iRECIST will be done in each center in order to choose the optimal therapy (Assessment by Investigators). A centralized evaluation of RECIST and iRECIST, will be organized in Saint-Antoine (Pr Yves Menu: central review) Primary endpoints: DCR at 12 weeks by RECIST 1.1 and iRECIST

DISEASE(S): Metastatic Colorectal Cancer,Patients With Deficient Mmr And/or Msi Metastatic Colorectal Cancer Treated With Nivolumab And Ipilimumab

PROVIDER: 2537094 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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iRECIST Evaluation’s Relevance for DCR in MMR/MSI Metastatic Colorectal Cancer Patients on Nivolumab and Ipilimumab

Project description:This is a non-randomized study, open label phase II study. The purpose of this study is to evaluate disease control rate (DCR) by RECIST and iRECIST at 12 weeks. Evaluation of RECIST and iRECIST will be done in each center in order to choose the optimal therapy (Assessment by Investigators). A centralized evaluation of RECIST and iRECIST, will be organized in Saint-Antoine.

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2009-10-31 | E-GEOD-18806 | biostudies-arrayexpress

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