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The feasibility study of FOLFOX therapy in gastrointestinal cancer patients undergoing hemodialysis

ABSTRACT: Interventions: FOLFOX therapy;Antineoplastic Combined Chemotherapy Protocols Primary outcome(s): Part1 : Recommended starting dose Part2: Completion rate of chemotherapy Study Design: single arm study, open(masking not used), uncontrolled control, single assignment, treatment purpose

DISEASE(S): Esophageal Cancer, Gastric Cancer, Small Bowel Cancer, Colorectal Cancer

PROVIDER: 2615374 | ecrin-mdr-crc |

REPOSITORIES: ECRIN MDR

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Exploring MicroRNA Patterns as Biomarkers of FOLFOX Chemotherapy-Induced Peripheral Neuropathy in Patients with Colorectal Cancer

Project description:This study aimed to identify potential miRNA-based biomarkers that can predict FOLFOX-CIPN symptoms. High throughput microRNA sequencing was performed on the RNA circulating in the plasma of eight patients with CRC who underwent FOLFOX chemotherapy. miRNA expression profiles were evaluated according to two groups: those who underwent ≤three cycles and those who underwent ≥six cycles of FOLFOX chemotherapy.

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Proteomic profiling of chemotherapy responses in FOLFOX-resistant colorectal cancer cells

Project description:we aim to compare the difference of chemotherapy responses between FOLFOX-resistant and wild type colorectal cancer cells for suggesting novel treatment targets.

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Global proteome changes in liver tissue 6 weeks after FOLFOX treatment of colorectal cancer liver metastases.

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2023-09-01 | E-MTAB-12949 | biostudies-arrayexpress

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